fleroxacin
Sign in to saveAlso known as Ro-236240, Ro-236240000, Megalone, Megalocin (TN), Megalocin, FLRX, Megalosin, Quinodis
Fleroxacin is a fluoroquinolone antibiotic. It is sold under the brand names Quinodis and Megalocin.
Research
674 papers- Fleroxacin clinical pharmacokinetics.Clinical pharmacokinetics · 1992
- Fleroxacin overview.Chemotherapy · 1996
- Photodegradation of fleroxacin by g-C(3)N(4)/PPy/Ag and HPLC-MS/MS analysis of degradation pathways.RSC advances · 2023
- Fleroxacin. A review of its pharmacology and therapeutic efficacy in various infections.Drugs · 1995
- [Fleroxacin--a new quinolone antibiotic].Vojnosanitetski pregled · 1996
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 369.13
- Has use
- medication
Show 4 more facts
- chemical formula
- C₁₇H₁₈F₃N₃O₃
- canonical SMILES
- CN1CCN(CC1)C2=C(C=C3C(=C2F)N(C=C(C3=O)C(=O)O)CCF)F
- World Health Organisation international non-proprietary name
- fleroxacin
- Commons category
- Fleroxacin
via Wikidata · CC0
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Encyclopedic overview
6 sectionsContents
- Mechanism of action
- Pharmacokinetics
- Medical uses
- Adverse effects
- Contraindications
- References
Fleroxacin is a fluoroquinolone antibiotic. It is sold under the brand names Quinodis and Megalocin.
== Mechanism of action == Fleroxacin is a bactericidal drug that inhibits bacterial DNA gyrase and topoisomerase IV. Like other quinolones and fluoroquinolones the compound eradicates bacteria by interfering with DNA replication (bacterial DNA replication, transcription, repair and recombination). Fleroxacin is active against many Gram-positive and Gram-negative bacteria. It is especially active against Shigella species., Salmonella sp., Escherichia coli, Moraxella catarrhalis, Haemophilus influenzae, Neisseria gonorrhoeae, Yersinia enterocolitica, Serratia marcescens, Staphylococcus aureus, Pseudomonas aeruginosa.
Excerpted from Wikipedia’s “fleroxacin” article, available under the CC BY-SA 4.0 licence.
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