flubendazole
Sign in to saveAlso known as R-17889, R 17899, Methyl N-(5-(p-fluorobenzoyl)-2-benzimidazolyl)carbamate, methyl 5-(p-fluorobenzoyl)-2-benzimidazolecarbamate, R 17,889, (5-(4-fluorobenzoyl)-1H-benzimidazole-2-yl)carbamic acid methyl ester
Flubendazole is an anthelmintic, used both in humans and for veterinarian purposes. It is very close chemically to mebendazole, the only difference being an added fluorine atom. Like mebendazole, flubendazole inhibits tubulin polymerization.
Research
427 papers- Flubendazole as a macrofilaricide: History and background.PLoS neglected tropical diseases · 2019
- Flubendazole Plays an Important Anti-Tumor Role in Different Types of Cancers.International journal of molecular sciences · 2022
- Anticancer role of flubendazole: Effects and molecular mechanisms (Review).Oncology letters · 2024
- Repurposing flubendazole for glioblastoma ferroptosis by affecting xCT and TFRC proteins.Journal of cellular and molecular medicine · 2024
- Anthelmintic Flubendazole and Its Potential Use in Anticancer Therapy.Acta medica (Hradec Kralove) · 2017
via PubMed
Wikidata facts
- Mass
- 313.086269
Show 6 more facts
- Commons category
- Flubendazole
- MCN code
- 2933.99.55
- chemical formula
- C₁₆H₁₂FN₃O₃
- canonical SMILES
- COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=C(C=C3)F
- World Health Organisation international non-proprietary name
- flubendazole
- defined daily dose
- 0.2
Sources (3)
via Wikidata · CC0
~2 min read
Article
3 sectionsContents
- Human use
- Veterinarian use
- References
Flubendazole is an anthelmintic, used both in humans and for veterinarian purposes. It is very close chemically to mebendazole, the only difference being an added fluorine atom. Like mebendazole, flubendazole inhibits tubulin polymerization.
__TOC__ == Human use ==