Structure via PubChem · Public domain (PubChem)
doramectin
Sign in to saveDoramectin, sold under the brand name Dectomax among others, is a veterinary medication approved by the US Food and Drug Administration (FDA) for the treatment of parasites such as gastrointestinal roundworms, lungworms, eyeworms, grubs, sucking lice, and mange mites in cattle. It is available as a generic medication. It is available as a combination with levamisole under the brand name Valcor.
Chemical data
- Formula
- C50H74O14
- Molecular weight
- 899.1 g/mol
- IUPAC name
- (1'R,2R,3S,4'S,6S,8'R,10'E,13'S,14'E,16'E,20'R,21'R,24'S)-2-cyclohexyl-21',24'-dihydroxy-12'-[(2R,4S,6S)-5-[(2S,4S,5S,6S)-5-hydroxy-4-methoxy-6-methyloxan-2-yl]oxy-4-methoxy-6-methyloxan-2-yl]oxy-3,11',13',22'-tetramethylspiro[2,3-dihydropyran-6,6'-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene]-2'-one
- SMILES
- C[C@H]1C=C[C@]2(C[C@@H]3C[C@H](O2)C/C=C(/C([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H](C([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)O[C@@H]1C8CCCCC8
- InChIKey
- QLFZZSKTJWDQOS-NJPOTTGESA-N
- XLogP
- 4.5
- Polar surface area
- 170 Ų
- H-bond donors
- 3
- H-bond acceptors
- 14
- Formal charge
- 0
via PubChem
Research
521 papers- Ivermectin, a potential anticancer drug derived from an antiparasitic drug.Pharmacological research · 2021
- Doramectin attenuates inflammation, obesity and insulin resistance in food-borne obese mice.Biochemical and biophysical research communications · 2024
- Doramectin--a novel avermectin.Veterinary parasitology · 1993
- Doramectin Induces Apoptosis in B16 Melanoma Cells.Anti-cancer agents in medicinal chemistry · 2025
- Repurposing of Doramectin as a New Anti-Zika Virus Agent.Viruses · 2023
via PubMed
Wikidata facts
- Subclass of
- macrolides
- Mass
- 898.507857
Show 6 more facts
- chemical formula
- C₅₀H₇₄O₁₄
- canonical SMILES
- CC1C=CC=C2COC3C2(C(C=C(C3O)C)C(=O)OC4CC(CC=C(C1OC5CC(C(C(O5)C)OC6CC(C(C(O6)C)O)OC)OC)C)OC7(C4)C=CC(C(O7)C8CCCCC8)C)O
- Commons category
- Doramectin
- isomeric SMILES
- C[C@H]1C=C[C@]2(C[C@@H]3C[C@H](O2)C/C=C(/C([C@H](/C=C/C=C/4\CO[C@H]5[C@@]4([C@@H](C=C([C@H]5O)C)C(=O)O3)O)C)O[C@H]6C[C@@H](C([C@@H](O6)C)O[C@H]7C[C@@H]([C@H]([C@@H](O7)C)O)OC)OC)\C)O[C@@H]1C8CCCCC8
- subject has role
- anxiolytic
- found in taxon
- Streptomyces avermitilis
via Wikidata · CC0
~4 min read
Encyclopedic overview
4 sectionsContents
- Society and culture
- Legal status
- Brand names
- References
{{Drugbox | verifiedrevid = 447193442 | image = Doramectin.svg | image_class = skin-invert-image | width = 300 | alt = | image2 = Doramectin2.png | image_class2 = bg-transparent | width2 = 250 | alt2 =
| pronounce = | tradename = Dectomax, others | Drugs.com = | MedlinePlus = | DailyMedID = Doramectin | pregnancy_AU = | pregnancy_AU_comment = | pregnancy_category = | routes_of_administration = Subcutaneous, intramuscular, topical | class = | ATCvet = yes | ATC_prefix = P54 | ATC_suffix = AA03 | ATC_supplemental =
Excerpted from Wikipedia’s “doramectin” article, available under the CC BY-SA 4.0 licence.
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via Wikidata sitelinks · CC0