Structure via PubChem · Public domain (PubChem)
OverviewAI-generated
Flunitrazepam is a chemical compound with the formula C₁₆H₁₂FN₃O₃. Its IUPAC name is 5-(2-fluorophenyl)-1-methyl-7-nitro-3H-1,4-benzodiazepin-2-one. The substance has a molecular weight of 313.28 and a mass of 313.086269. It carries an MCN code of 2933.91.32 and a defined daily dose of 1.
Physicochemical properties include an xlogp of 2.1, a topological polar surface area of 78.5, and a charge of 0. The molecule contains zero hydrogen bond donors and five hydrogen bond acceptors. Flunitrazepam is the subject of 3,840 PubMed entries and is referenced by 944 other encyclopedia articles.
Synthesized by Vinony from 19 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Key facts
- Drug.Watchedfields
- changed
- Drug.class
- Benzodiazepine
- Drug.verifiedrevid
- 477167367
- Drug.IUPAC_name
- 5-(2-fluorophenyl)-1-methyl-7-nitro-1H-benzo[e][1,4]diazepin-2(3H)-one
- Drug.image
- Flunitrazepam structure.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 200
- Drug.image2
- Flunitrazepam-from-xtal-3D-balls.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Rohypnol
- Drug.pregnancy_AU
- C
- Drug.legal_AU
- S8
- Drug.legal_BR
- B1
- Drug.legal_CA
- Schedule I
- Drug.legal_DE
- Anlage III
- Drug.legal_UK
- Class C
- Drug.legal_US
- Schedule IV (Schedule I trafficking penalties, however)
- Drug.legal_UN
- Psychotropic Schedule III
via Wikipedia infobox
Chemical data
- Formula
- C16H12FN3O3
- Molecular weight
- 313.28 g/mol
- IUPAC name
- 5-(2-fluorophenyl)-1-methyl-7-nitro-3H-1,4-benzodiazepin-2-one
- SMILES
- CN1C(=O)CN=C(C2=C1C=CC(=C2)[N+](=O)[O-])C3=CC=CC=C3F
- InChIKey
- PPTYJKAXVCCBDU-UHFFFAOYSA-N
- XLogP
- 2.1
- Polar surface area
- 78.5 Ų
- H-bond donors
- 0
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Research
3,840 papersvia PubMed
Article · Italiano
Il flunitrazepam appartiene alla classe delle benzodiazepine; sintetizzato agli inizi degli anni settanta dagli stabilimenti Hoffmann-La Roche (con il nome commerciale Rohypnol o Roophis), ha conosciuto inizialmente un uso ospedaliero nei casi in cui era richiesta la sedazione profonda. È entrato nel mercato commerciale in Europa nel 1975 e negli anni ottanta ha cominciato a essere disponibile in altri paesi. Solo agli inizi degli anni novanta è stato introdotto negli Stati Uniti. In Italia è venduto, dietro presentazione di ricetta medica ministeriale a ricalco, con il nome commerciale di Roipnol.
Abstract from DBpedia / Wikipedia · CC BY-SA