Structure via PubChem · Public domain (PubChem)
OverviewAI-generated
Flunitrazepam is a chemical compound with the formula C₁₆H₁₂FN₃O₃. Its IUPAC name is 5-(2-fluorophenyl)-1-methyl-7-nitro-3H-1,4-benzodiazepin-2-one. The substance has a molecular weight of 313.28 and a mass of 313.086269. It carries an MCN code of 2933.91.32 and a defined daily dose of 1.
Physicochemical properties include an xlogp of 2.1, a topological polar surface area of 78.5, and a charge of 0. The molecule contains zero hydrogen bond donors and five hydrogen bond acceptors. Flunitrazepam is the subject of 3,840 PubMed entries and is referenced by 944 other encyclopedia articles.
Synthesized by Vinony from 19 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Key facts
- Drug.Watchedfields
- changed
- Drug.class
- Benzodiazepine
- Drug.verifiedrevid
- 477167367
- Drug.IUPAC_name
- 5-(2-fluorophenyl)-1-methyl-7-nitro-1H-benzo[e][1,4]diazepin-2(3H)-one
- Drug.image
- Flunitrazepam structure.svg
- Drug.image_class
- skin-invert-image
- Drug.width
- 200
- Drug.image2
- Flunitrazepam-from-xtal-3D-balls.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Rohypnol
- Drug.pregnancy_AU
- C
- Drug.legal_AU
- S8
- Drug.legal_BR
- B1
- Drug.legal_CA
- Schedule I
- Drug.legal_DE
- Anlage III
- Drug.legal_UK
- Class C
- Drug.legal_US
- Schedule IV (Schedule I trafficking penalties, however)
- Drug.legal_UN
- Psychotropic Schedule III
via Wikipedia infobox
Chemical data
- Formula
- C16H12FN3O3
- Molecular weight
- 313.28 g/mol
- IUPAC name
- 5-(2-fluorophenyl)-1-methyl-7-nitro-3H-1,4-benzodiazepin-2-one
- SMILES
- CN1C(=O)CN=C(C2=C1C=CC(=C2)[N+](=O)[O-])C3=CC=CC=C3F
- InChIKey
- PPTYJKAXVCCBDU-UHFFFAOYSA-N
- XLogP
- 2.1
- Polar surface area
- 78.5 Ų
- H-bond donors
- 0
- H-bond acceptors
- 5
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
Withdrawn- Max clinical phase
- Approved
- Molecule type
- Small molecule
- Admin. routes
- oral
via ChEMBL · EBI
Research
3,840 papersvia PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 313.086269
- Has use
- medication
Show 6 more facts
- Commons category
- Flunitrazepam
- chemical formula
- C₁₆H₁₂FN₃O₃
- World Health Organisation international non-proprietary name
- flunitrazepam
- canonical SMILES
- CN1C(=O)CN=C(C2=C1C=CC(=C2)[N+](=O)[O-])C3=CC=CC=C3F
- defined daily dose
- 1
- MCN code
- 2933.91.32
via Wikidata · CC0
Article · 中文
氟硝西泮（学名：Flunitrazepam）常稱FM2、羅眠樂、氟硝安定、氟硝基安定、氟甲硝安定、十字架、十字仔，由羅氏藥廠制造，取它們的成分Flunitrazepam的首尾字母加原劑型每錠兩毫克而簡稱為「FM2」。为一种精神药品，强度微烈、麻醉前用藥、安眠药。瑞士藥廠也為其推出美得眠（Modipanol），一樣是需要醫囑開立的管制藥品。自2017年7月之後，瑞士藥廠生產的FM2更名為「服爾眠」（Fallep），原先藥錠兩面皆為十字印記，修改為一面維持十字刻痕，另一面是數字2。 中樞神經抑制劑中的苯二氮平類（Benzodiazepines）中的一種，苯二氮平類可讓大腦的GABA接受體與GABA相結合，因而讓氯離子通道讓大量的氯離子進入細胞而降低中樞神經活性所以起到了抑制和鎮靜作用，主要是作用在網狀活化系統和大腦皮質，苯二氮平類（Benzodiazepines）可以分為長中短效三型而FM2為長效型。此藥的解藥是（Flumazenil/氟馬西尼/安易醒）。
Abstract from DBpedia / Wikipedia · CC BY-SA