GABPA

Name

GA binding protein transcription factor subunit alpha

Type

protein-coding

Position

25,734,570–25,772,460 (+)

Aliases

E4TF1-60, E4TF1A, NFT2, NRF2, NRF2A, RCH04A07

Ensembl

ENSG00000154727

RefSeq RNA

NM_001197297.2, NM_002040.4, XM_005260938.6, XM_017028313.3, XM_024452062.2

RefSeq protein

NP_001184226.1, NP_002031.2, XP_005260995.1, XP_016883802.1, XP_024307830.1

This gene encodes one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, this gene may play a role in the Down Syndrome phenotype. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Oct 2010].

via MyGene.info

Gene · Ensembl

GA binding protein transcription factor subunit alpha

Symbol

GABPA

Biotype

Protein coding

Organism

Homo sapiens

Location

21:25,734,570-25,772,460

Strand

Forward (+)

Assembly

GRCh38