ژستودن

Also known as SH B 331, SID144205785, SH b 331

Gestodene, sold under the brand names Femodene and Minulet among others, is a progestin medication which is used in birth control pills for women. It is also used in menopausal hormone therapy. The medication is available almost exclusively in combination with an estrogen. It is taken by mouth.

Chemical data

Formula: C21H26O2
Molecular weight: 310.4 g/mol
IUPAC name: (8R,9S,10R,13S,14S,17R)-13-ethyl-17-ethynyl-17-hydroxy-1,2,6,7,8,9,10,11,12,14-decahydrocyclopenta[a]phenanthren-3-one
SMILES: CC[C@]12CC[C@H]3[C@H]([C@@H]1C=C[C@]2(C#C)O)CCC4=CC(=O)CC[C@H]34
InChIKey: SIGSPDASOTUPFS-XUDSTZEESA-N
XLogP: 2.9
Polar surface area: 37.3 Å²
H-bond donors: 1
H-bond acceptors: 2
Formal charge: 0

via PubChem

Drug data · ChEMBL

Max clinical phase: Phase 3
Molecule type: Small molecule

via ChEMBL · EBI

Research

929 papers

Gestodene-containing contraceptives.Clinical obstetrics and gynecology · 1995
Gestodene: a review of its pharmacology, potency and tolerability in combined contraceptive preparations.Contraception · 2014
Combined oral contraceptives: venous thrombosis.The Cochrane database of systematic reviews · 2014
Gestodene. A review of its pharmacology, efficacy and tolerability in combined contraceptive preparations.Drugs · 1995
New progestins--clinical experiences: gestodene.American journal of obstetrics and gynecology · 1994

via PubMed

Wikidata facts

Mass: 310.193
Has use: medication

Show 7 more facts

chemical formula: C₂₁H₂₆O₂
World Health Organisation international non-proprietary name: gestodene
isomeric SMILES: CC[C@]12CC[C@H]3[C@H]([C@@H]1C=C[C@]2(C#C)O)CCC4=CC(=O)CC[C@H]34
canonical SMILES: CCC12CCC3C(C1C=CC2(C#C)O)CCC4=CC(=O)CCC34
subject has role: 5-alpha-reductase inhibitors
MCN code: 2937.23.92
Commons category: Gestodene

Sources (3)

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Gallery (2)

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