Structure via PubChem · Public domain (PubChem)
گلوتتیمید
Sign in to saveAlso known as Doriden®, 2-Ethyl-2-phenylglutarimide, Doriden, Glutethimide
Glutethimide (brand names included Doriden, Elrodorm, and Noxyron) is a central nervous system (CNS) depressant drug of the piperidine chemical class, one of many non-barbiturate, "barbiturate-like" GABAergic medications exhibiting general calming, relaxing, or "tranquilizing" properties in addition to relieving anxiety and promoting sleep. As such, "nerve pills" or "sleeping pills" were common vernacular descriptions of these types of medications.
Chemical data
- Formula
- C13H15NO2
- Molecular weight
- 217.26 g/mol
- IUPAC name
- 3-ethyl-3-phenylpiperidine-2,6-dione
- SMILES
- CCC1(CCC(=O)NC1=O)C2=CC=CC=C2
- InChIKey
- JMBQKKAJIKAWKF-UHFFFAOYSA-N
- XLogP
- 1.9
- Polar surface area
- 46.2 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1976
- Admin. routes
- oral
via ChEMBL · EBI
Research
2,279 papers- Glutethimide (Doriden) poisoning. Controversies in treatment.Arizona medicine · 1971
- Glutethimide rebound.Lancet (London, England) · 1970
- [Glutethimide poisoning (alpha-phenylo-alpha-ethylo-glutaric acid imide)].Polski tygodnik lekarski (Warsaw, Poland : 1960) · 1966
- Glutethimide abuse.The American journal of psychiatry · 1982
- Chronic glutethimide abuse.The British journal of clinical practice · 1986
via PubMed
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 217.110279
- Has use
- medication
Show 6 more facts
- chemical formula
- C₁₃H₁₅NO₂
- World Health Organisation international non-proprietary name
- glutethimide
- medical condition treated
- insomnia
- canonical SMILES
- CCC1(CCC(=O)NC1=O)C2=CC=CC=C2
- defined daily dose
- 0.25
- Commons category
- Glutethimide
via Wikidata · CC0