GPR160
Sign in to saveAlso known as GPCR1, GPCR150, G protein-coupled receptor 160
Probable G-protein coupled receptor 160 is a protein that in humans is encoded by the GPR160 gene. It has been shown to be important in embryonic stem cell development, is involved in the perception of neuropathic pain, and is present in elevated levels in some cancers. GPR160 has been suggested as the receptor for Cocaine- and amphetamine-regulated transcript, also known as CART. However other research has since shown that it does not appear CART binds to GPR160 directly. This suggests that an as yet unidentified target for CART may modulate GPR160 mediated responses indirectly under certain
Gene data
GPR160- Name
- G protein-coupled receptor 160
- Type
- protein-coding
- Position
- 170,037,451–170,089,944 (+)
- Aliases
- GPCR1, GPCR150
- Ensembl
- ENSG00000173890
- RefSeq RNA
- NM_014373.3, XM_005247346.5, XM_005247347.5, XM_017006161.3, XM_024453449.2
- RefSeq protein
- NP_055188.1, XP_005247403.1, XP_005247404.1, XP_016861650.1, XP_024309217.1
Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Located in plasma membrane. Part of receptor complex. [provided by Alliance of Genome Resources, Apr 2022]
Gene Ontology
Molecular function
via MyGene.info
Gene · Ensembl
G protein-coupled receptor 160
- Symbol
- GPR160
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 3:170,037,451-170,089,944
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 8659
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/26996
- genomic end
- 170085392
- genomic start
- 170037995
- chromosome
- human chromosome 3
- cytogenetic location
- 3q26.2
- expressed in
- trabecular bone
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Probable G-protein coupled receptor 160 is a protein that in humans is encoded by the GPR160 gene. It has been shown to be important in embryonic stem cell development, is involved in the perception of neuropathic pain, and is present in elevated levels in some cancers. GPR160 has been suggested as the receptor for Cocaine- and amphetamine-regulated transcript, also known as CART. However other research has since shown that it does not appear CART binds to GPR160 directly. This suggests that an as yet unidentified target for CART may modulate GPR160 mediated responses indirectly under certain conditions, but without directly binding to the GPR160 receptor.
== References ==
Excerpted from Wikipedia’s “GPR160” article, available under the CC BY-SA 4.0 licence.