British biochemist (born 1951)
Greg Winter is a British biochemist born in 1951 who developed techniques for producing antibodies in the laboratory, which has had major applications in medicine and disease treatment. His work earned him a share of the Nobel Prize in Chemistry and represents an important advance in how scientists can create therapeutic proteins to fight illness.
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Sir Gregory Paul Winter (born 14 April 1951) is a Nobel Prize–winning British molecular biologist best known for his work on the therapeutic use of monoclonal antibodies. His research career has been based almost entirely at the MRC Laboratory of Molecular Biology and the MRC Centre for Protein Engineering, in Cambridge, England.
He is credited with the invention of techniques to both humanize (1986) and, later, to fully humanize using phage display, antibodies for therapeutic uses. Previously, antibodies had been derived from mice, which made them difficult to use in human therapeutics because the human immune system had anti-mouse reactions to them. For these developments Winter was awarded the 2018 Nobel Prize in Chemistry along with George Smith and Frances Arnold.
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