GSDMB
Sign in to saveAlso known as GSDML, PRO2521, PP4052, gasdermin B, GSDMB-1
Gasdermin B is a protein that in humans is encoded by the GSDMB gene.
Gene data
GSDMB- Name
- gasdermin B
- Type
- protein-coding
- Position
- 39,904,595–39,919,854 (−)
- Aliases
- GSDMB-1, GSDML, PP4052, PRO2521
- Ensembl
- ENSG00000073605
- RefSeq RNA
- NM_001042471.2, NM_001165958.2, NM_001165959.2, NM_001369402.2, NM_001388420.1
- RefSeq protein
- NP_001035936.1, NP_001159430.1, NP_001159431.1, NP_001356331.1, NP_001375349.1
This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Alternative splicing and the use of alternative promoters results in multiple transcript variants. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding. [provided by RefSeq, Nov 2016].
Gene Ontology
Biological process
Molecular function
Cellular component
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 88856
- exact match
- identifiers.org/ncbigene/55876
- genomic end
- 38076107
- genomic start
- 38060848
- cytogenetic location
- 17q21.1
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Article
4 sectionsContents
- Function
- Clinical significance
- References
- Further reading
Gasdermin B is a protein that in humans is encoded by the GSDMB gene.
==Function==