File:Guanidin.svg · Wikimedia Commons · See Wikimedia Commons
گوانیدین
Sign in to saveAlso known as Gu, H2N-C(=NH)-NH2, carbamidine, imidourea, carbamamidine, aminoformamidine, aminomethanamidine, iminourea
Guanidine is the compound with the formula HNC(NH2)2. It is a colourless solid that dissolves in polar solvents. It is a strong base that is used in the production of plastics and explosives. It is found in urine predominantly in patients experiencing renal failure. A guanidine moiety also appears in larger organic molecules, including on the side chain of arginine.
OverviewAI-generated
Guanidine is a chemical compound with the formula CH₅N₃. It has a mass of 59.048 and a melting point of 50. The standard enthalpy of formation for the substance is -56.01. Its canonical SMILES notation is C(=N)(N)N.
Chemical properties include an xlogp value of -1.3 and a topological polar surface area of 75.9. The molecule contains three hydrogen bond donors and one hydrogen bond acceptor, with a charge of 0. The IUPAC name is guanidine.
The compound is referenced by 152 other encyclopedia articles. A search for guanidine in PubMed yields 101895 results.
Synthesized by Vinony from 22 facts across 4 sources: Wikidata, PubMed, PubChem, Vinony graph. Generated from structured data (not the Wikipedia text) and checked against those facts — may still contain errors.
Chemical data
- Formula
- CH5N3
- Molecular weight
- 59.07 g/mol
- IUPAC name
- guanidine
- SMILES
- C(=N)(N)N
- InChIKey
- ZRALSGWEFCBTJO-UHFFFAOYSA-N
- XLogP
- -1.3
- Polar surface area
- 75.9 Ų
- H-bond donors
- 3
- H-bond acceptors
- 1
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1939
- Admin. routes
- oral
- Indications
- neuroendocrine neoplasm, metastasis
via ChEMBL · EBI
Research
101,895 papers- Fused Tricyclic Guanidine Alkaloids: Insights into Their Structure, Synthesis and Bioactivity.Marine drugs · 2022
- Synthetic and natural guanidine derivatives as antitumor and antimicrobial agents: A review.Bioorganic chemistry · 2023
- Antifungal activity of guanidine compounds.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
- A variant of guanidine-IV riboswitches exhibits evidence of a distinct ligand specificity.RNA biology · 2023
- Unique guanidine-conjugated catechins from the leaves of Alchornea rugosa and their autophagy modulating activity.Phytochemistry · 2023
via PubMed
Wikidata facts
- Has part
- hydrogen
- Mass
- 59.048
- Has use
- medication
Show 8 more facts
- found in taxon
- Malus domestica
- Commons category
- Guanidine
- chemical formula
- CH₅N₃
- canonical SMILES
- C(=N)(N)N
- melting point
- 50
- standard enthalpy of formation
- -56.01
- MCN code
- 2925.29.21
- element symbol
- Gu
Sources (5)
via Wikidata · CC0