hepatocellular carcinoma

Also known as malignant hepatoma, HCC, Hepatoma, adult Hepatoma, adult primary hepatocellular carcinoma, Hepatocellular carcinoma, HCC, Adult Primary Liver Cell Carcinoma, Adult HCC

liver carcinoma that has material basis in undifferentiated hepatocytes

Key facts

Other names: Hepatoma
Specialty: Oncology
Symptoms: Loss of appetite, jaundice, nausea and vomiting, itching
Risk factors: Hepatitis B , hepatitis C , alcohol use disorder , cirrhosis , smoking

via Wikipedia infobox

Research

177,201 papers

via PubMed

Wikidata facts

Image: Hepatocellular carcinoma 1.jpg

Sources (7)

Article

Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer in adults and is currently the most common cause of death in people with cirrhosis. HCC is the third leading cause of cancer-related deaths worldwide.

HCC most commonly occurs in those with chronic liver disease especially those with cirrhosis or fibrosis, which occur in the setting of chronic liver injury and inflammation. HCC is rare in those without chronic liver disease. Chronic liver diseases which greatly increase the risk of HCC include hepatitis infection such as (hepatitis B, C or D), non-alcoholic steatohepatitis (NASH), alcoholic liver disease, or exposure to toxins such as aflatoxin, or pyrrolizidine alkaloids. Certain diseases, such as hemochromatosis and alpha 1-antitrypsin deficiency, markedly increase the risk of developing HCC. The five-year survival in those with HCC is 18%.