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GeneQ18059386· pop 5· linked from 2 articles

Also known as hepatocellular carcinoma, down-regulated 1

Hepatocellular carcinoma, down-regulated 1 is a protein that in humans is encoded by the HEPN1 gene.

Gene data

HEPN1
Name
hepatocellular carcinoma, down-regulated 1
Type
protein-coding

This gene is expressed predominantly in the liver. Transient transfection studies show the expression of this gene significantly inhibits cell growth, suggesting a role for this gene in apoptosis. Expression of this gene is down-regulated or lost in hepatocellular carcinomas (HCC), suggesting that loss of this gene is involved in carcinogenesis of hepatocytes (PMID:12971969). This gene maps to the 3'-noncoding region of the HEPACAM gene (GeneID:220296) on the antisense strand. [provided by RefSeq, Aug 2020].

via MyGene.info

Wikidata facts

Show 5 more facts
HomoloGene ID
134601
cytogenetic location
11q24.2
genomic start
124789089
genomic end
124806308
Sources (3)

via Wikidata · CC0

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Article

3 sections
Contents
  • Function
  • References
  • Further reading

Hepatocellular carcinoma, down-regulated 1 is a protein that in humans is encoded by the HEPN1 gene.

==Function==

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