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histiocyte
Sign in to savethumb | right | alt=Representative photographs of an open biopsy specimen (400x): a. Necrosis, usually with blurred cell shadow, was mixed with karyorrhexis and histiocytes. b. Numerous histiocytes engulfed karyorrhectic debris. c. Foamy histiocytes were identified. d. Immunohistochemical stain for CD123 highlighted plasmacytoid dendritic cells. Hematoxylin counterstain revealed abundant karyorrhexis around the plasmacytoid dendritic cells. | Representative photographs of an open biopsy specimen (400x): a. Necrosis, usually with blurred cell shadow, was mixed with karyorrhexis and histiocytes.
Key facts
- Cell.Name
- Histiocyte
- Cell.Latin
- macrophagocytus immobilis
- Cell.System
- Immune system
via Wikipedia infobox
Article
7 sectionsContents
- Development
- Structure
- Macrophages and dendritic cells
- Langerhans cells
- Clinical significance
- See also
- References
thumb | right | alt=Representative photographs of an open biopsy specimen (400x): a. Necrosis, usually with blurred cell shadow, was mixed with karyorrhexis and histiocytes. b. Numerous histiocytes engulfed karyorrhectic debris. c. Foamy histiocytes were identified. d. Immunohistochemical stain for CD123 highlighted plasmacytoid dendritic cells. Hematoxylin counterstain revealed abundant karyorrhexis around the plasmacytoid dendritic cells. | Representative photographs of an open biopsy specimen (400x): a. Necrosis, usually with blurred cell shadow, was mixed with karyorrhexis and histiocytes. b. Numerous histiocytes engulfed karyorrhectic debris. c. Foamy histiocytes were identified. d. Immunohistochemical stain for CD123 highlighted plasmacytoid dendritic cells. Hematoxylin counterstain revealed abundant karyorrhexis around the plasmacytoid dendritic cells. A histiocyte is a vertebrate cell that is part of the mononuclear phagocyte system (also known as the reticuloendothelial system or lymphoreticular system). The mononuclear phagocytic system is part of the organism's immune system. The histiocyte is a tissue macrophage or a dendritic cell (histio, diminutive of histo, meaning tissue, and cyte, meaning cell). Part of their job is to clear out neutrophils once they've reached the end of their lifespan.
==Development== Histiocytes are derived from the bone marrow by multiplication from a stem cell. The derived cells migrate from the bone marrow to the blood as monocytes. They circulate through the body and enter various organs, where they undergo differentiation into histiocytes, which are part of the mononuclear phagocytic system (MPS).