platelet
Sign in to savePlatelets or thrombocytes () are a part of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping to form a blood clot. Platelets have no cell nucleus; they are fragments of cytoplasm from megakaryocytes which reside in bone marrow or lung tissue, and then enter the circulation. Platelets are found only in mammals, whereas in other vertebrates (e.g. birds, amphibians), thrombocytes circulate as intact mononuclear cells.
AI overview
Platelets are tiny fragments in your blood that work together with other clotting factors to stop bleeding by forming clots when blood vessels are injured. These cell fragments come from larger cells in your bone marrow and lungs, and unlike thrombocytes in other animals, mammalian platelets lack a nucleus.
AI-generated from the Wikipedia summary — may contain errors.
Key facts
- Cell.Name
- Platelets
- Cell.Latin
- thrombocytus
- Cell.Image
- Platelets2.JPG
- Cell.Caption
- Image from a light microscope (500 ×) from a Giemsa-stained peripheral blood smear showing platelets (small purple dots) surrounded by red blood cells (large gray circular structures)
- Cell.Precursor
- Megakaryocytes
- Cell.Function
- Formation of blood clots; prevention of bleeding
via Wikipedia infobox
Article
47 sectionsContents
- Term
- Structure
- Shape
- Development
- Hemostasis
- Adhesion
- Activation
- Inhibition
- Trigger (induction)
- Components (consequences)
- GPIIb/IIIa activation
- Granule secretion
- Morphology change
- Platelet-coagulation factor interactions: coagulation facilitation
- Immune function
- Immunothrombosis
- Inflammation
- Adaptive immunity
- Measurement and testing
- Measurement
- Bleeding time
- Multiple electrode aggregometry
- Light transmission aggregometry
- Whole blood impedance aggregometry
- PFA-100
- Clinical significance
- Disorders
- Thrombocytopenia
- Altered platelet function
- Thrombocytosis and thrombocythemia
- Pharmacology
- Anti-inflammatory drugs
- Drugs that suppress platelet function
- Oral agents
- Intravenous agents
- Drugs that stimulate platelet production
- Therapies
- Transfusion
- Indications
- Collection
- Storage
- Delivery
- Wound repair
- Non-mammals
- History
- See also
- References
Platelets or thrombocytes () are a part of blood whose function (along with the coagulation factors) is to react to bleeding from blood vessel injury by clumping to form a blood clot. Platelets have no cell nucleus; they are fragments of cytoplasm from megakaryocytes which reside in bone marrow or lung tissue, and then enter the circulation. Platelets are found only in mammals, whereas in other vertebrates (e.g. birds, amphibians), thrombocytes circulate as intact mononuclear cells.
thumb|The ligands, denoted by letter L, signal for platelets (P) to migrate towards the wound (Site A). As more platelets gather around the opening, they produce more ligands to amplify the response. The platelets congregate around the wound in order to create a cap to stop blood flow out of the tissue.