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GeneQ18046363· pop 5· linked from 83 articles

Also known as BLOC2S3, HPS6, biogenesis of lysosomal organelles complex 2 subunit 3, HPS6 biogenesis of lysosomal organelles complex 2 subunit 3

Hermansky–Pudlak syndrome 6 (HPS6), also known as ruby-eye protein homolog (Ru), is a protein that in humans is encoded by the HPS6 gene.

Gene data

HPS6
Name
HPS6 biogenesis of lysosomal organelles complex 2 subunit 3
Type
protein-coding
Aliases
BLOC2S3

This intronless gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. This protein interacts with Hermansky-Pudlak syndrome 5 protein. Mutations in this gene are associated with Hermansky-Pudlak syndrome type 6. [provided by RefSeq, Jul 2008].

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HPS6 biogenesis of lysosomal organelles complex 2 subunit 3

Symbol
HPS6
Biotype
Protein coding
Organism
Homo sapiens
Location
10:102,065,349-102,068,036
Strand
Forward (+)
Assembly
GRCh38
View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Show 5 more facts
HomoloGene ID
11691
genomic end
102068036
genomic start
102065349
cytogenetic location
10q24.32
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Article

5 sections
Contents
  • Function
  • Clinical significance
  • References
  • Further reading
  • External links

Hermansky–Pudlak syndrome 6 (HPS6), also known as ruby-eye protein homolog (Ru), is a protein that in humans is encoded by the HPS6 gene.

== Function == This intronless gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. HPS6 along with HPS3 and HPS5 form a stable protein complex named Biogenesis of Lysosome-related Organelles Complex-2 (BLOC-2).

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