PDXK
Sign in to saveAlso known as C21orf124, C21orf97, HEL-S-1a, PKH, PNK, PRED79, pyridoxal (pyridoxine, vitamin B6) kinase, pyridoxal kinase
Pyridoxal kinase is an enzyme that in humans is encoded by the PDXK gene.
In the Vinony graph
Within Vinony's link graph, PDXK is referenced by 5 other articles, and connects out to PubMed, human chromosome 21 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 21.
Its subject is documented across 5 Wikipedia language editions.
Gene data
PDXK- Name
- pyridoxal kinase
- Type
- protein-coding
- Position
- 43,719,061–43,762,307 (+)
- Aliases
- C21orf124, C21orf97, HEL-S-1a, HMSN6C, PKH, PNK, PRED79
- Ensembl
- ENSG00000160209
- RefSeq RNA
- NM_001331030.2, NM_003681.5, NM_021941.1, XM_005261195.3, XM_005261196.4
- RefSeq protein
- NP_001317959.1, NP_003672.1, XP_005261252.2, XP_005261253.1, XP_005261256.1
The protein encoded by this gene phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
pyridoxal kinase
- Symbol
- PDXK
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 21:43,719,061-43,762,307
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein PDXK PDB 2ajp.png
Show 8 more facts
- HomoloGene ID
- 2731
- exact match
- identifiers.org/ncbigene/8566
- found in taxon
- Homo sapiens
- genomic end
- 45182188
- genomic start
- 45138975
- chromosome
- human chromosome 21
- cytogenetic location
- 21q22.3
- expressed in
- nucleus accumbens
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- Further reading
Pyridoxal kinase is an enzyme that in humans is encoded by the PDXK gene.
The protein encoded by this gene phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Excerpted from Wikipedia’s “PDXK” article, available under the CC BY-SA 4.0 licence.