PDXK
Sign in to saveAlso known as C21orf124, C21orf97, HEL-S-1a, PKH, PNK, PRED79, pyridoxal (pyridoxine, vitamin B6) kinase, pyridoxal kinase
Pyridoxal kinase is an enzyme that in humans is encoded by the PDXK gene.
Gene data
PDXK- Name
- pyridoxal kinase
- Type
- protein-coding
- Aliases
- C21orf124, C21orf97, HEL-S-1a, HMSN6C, PKH, PNK, PRED79
The protein encoded by this gene phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
via MyGene.info
Gene · Ensembl
pyridoxal kinase
- Symbol
- PDXK
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 21:43,719,061-43,762,307
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Image
- Protein PDXK PDB 2ajp.png
Show 5 more facts
- HomoloGene ID
- 2731
- exact match
- identifiers.org/ncbigene/8566
- genomic end
- 45182188
- genomic start
- 45138975
- cytogenetic location
- 21q22.3
Sources (4)
via Wikidata · CC0
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Article
2 sectionsContents
- References
- Further reading
Pyridoxal kinase is an enzyme that in humans is encoded by the PDXK gene.
The protein encoded by this gene phosphorylates vitamin B6, a step required for the conversion of vitamin B6 to pyridoxal-5-phosphate, an important cofactor in intermediary metabolism. The encoded protein is cytoplasmic and probably acts as a homodimer. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.