Structure via PubChem · Public domain (PubChem)
huperzine A
Sign in to saveAlso known as (−)-huperazine A, (−)-selagine, L-huperzine A, selagine, (-)-huperazine A, (-)-selagine
chemical compound
Chemical data
- Formula
- C15H18N2O
- Molecular weight
- 242.32 g/mol
- IUPAC name
- (1R,9R,13E)-1-amino-13-ethylidene-11-methyl-6-azatricyclo[7.3.1.02,7]trideca-2(7),3,10-trien-5-one
- SMILES
- C/C=C/1\[C@@H]2CC3=C([C@]1(CC(=C2)C)N)C=CC(=O)N3
- InChIKey
- ZRJBHWIHUMBLCN-YQEJDHNASA-N
- XLogP
- 0
- Polar surface area
- 55.1 Ų
- H-bond donors
- 2
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
- Indications
- substance abuse, brain injury, Alzheimer disease, cocaine abuse
via ChEMBL · EBI
Research
772 papers- Huperzine A and Its Neuroprotective Molecular Signaling in Alzheimer's Disease.Molecules (Basel, Switzerland) · 2021
- Huperzine A.Drugs in R&D · 2004
- Ginkgolides and Huperzine A for complementary treatment of Alzheimer's disease.IUBMB life · 2022
- Delineating biosynthesis of Huperzine A, A plant-derived medicine for the treatment of Alzheimer's disease.Biotechnology advances · 2022
- Huperzine A.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2000
via PubMed
Wikidata facts
- Mass
- 242.142
Show 6 more facts
- chemical formula
- C₁₅H₁₈N₂O
- found in taxon
- Phlegmariurus varius
- canonical SMILES
- CC=C1C2CC3=C(C1(CC(=C2)C)N)C=CC(=O)N3
- isomeric SMILES
- C/C=C/1\[C@@H]2CC3=C([C@]1(CC(=C2)C)N)C=CC(=O)N3
- subject has role
- nootropic
- Commons category
- Huperzine A
via Wikidata · CC0