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GeneQ18027578· pop 5· linked from 7 articles

Also known as G10P2, GARG-39, IFI-54, IFI-54K, IFI54, IFIT-2, ISG-54 K, ISG-54K

Interferon-induced protein with tetratricopeptide repeats 2 (commonly termed IFIT2) is a protein that in humans is directed to be produced by the IFIT2 gene. Previously, this gene was termed the G10P2, GARG-39, IFI-54, IFI-54K, IFI54, IFIT-2, ISG-54 K, ISG-54K, ISG54, or P54 gene and the protein that it directs to be produced was termed the G10P2, GARG-39, IFI-54, IFI-54K, IFI54, IFIT-2, ISG-54 K, ISG-54K, ISG54, or P54 protein. The IFIT2 gene is one of the many genes that are stimulated by type 1 interferons to form their messenger RNAs and thereby their product proteins. Consequently, the IF

Gene data

IFIT2
Name
interferon induced protein with tetratricopeptide repeats 2
Type
protein-coding
Aliases
G10P2, GARG-39, IFI-54, IFI-54K, IFI54, IFIT-2, ISG-54, ISG-54 K, ISG-54K, ISG54

Enables RNA binding activity. Involved in negative regulation of protein binding activity; positive regulation of apoptotic process; and response to virus. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Apr 2022]

via MyGene.info

Wikidata facts

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HomoloGene ID
1187
genomic end
89309271
genomic start
91061712
cytogenetic location
10q23.31
Sources (4)

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~1 min read

Article

3 sections
Contents
  • Clinical significance
  • References
  • Further reading

Interferon-induced protein with tetratricopeptide repeats 2 (commonly termed IFIT2) is a protein that in humans is directed to be produced by the IFIT2 gene. Previously, this gene was termed the G10P2, GARG-39, IFI-54, IFI-54K, IFI54, IFIT-2, ISG-54 K, ISG-54K, ISG54, or P54 gene and the protein that it directs to be produced was termed the G10P2, GARG-39, IFI-54, IFI-54K, IFI54, IFIT-2, ISG-54 K, ISG-54K, ISG54, or P54 protein. The IFIT2 gene is one of the many genes that are stimulated by type 1 interferons to form their messenger RNAs and thereby their product proteins. Consequently, the IFIT2 gene is classified as one of the many type 1 interferon-stimulated genes.

== Clinical significance ==

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