IFNGR1
Sign in to saveAlso known as CD119, IFNGR, IMD27A, IMD27B, interferon gamma receptor 1
protein-coding gene in the species Homo sapiens
Gene data
IFNGR1- Name
- interferon gamma receptor 1
- Type
- protein-coding
- Position
- 137,197,483–137,219,449 (−)
- Aliases
- CD119, IFNGR, IMD27A, IMD27B
- Ensembl
- ENSG00000027697
- RefSeq RNA
- NM_000416.3, NM_001363526.1, NM_001363527.1, XM_006715470.4, XM_011535793.3
- RefSeq protein
- NP_000407.1, NP_001350455.1, NP_001350456.1, XP_006715533.1, XP_011534095.1
This gene (IFNGR1) encodes the ligand-binding chain (alpha) of the gamma interferon receptor. Human interferon-gamma receptor is a heterodimer of IFNGR1 and IFNGR2. A genetic variation in IFNGR1 is associated with susceptibility to Helicobacter pylori infection. In addition, defects in IFNGR1 are a cause of mendelian susceptibility to mycobacterial disease, also known as familial disseminated atypical mycobacterial infection. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Pathways
Cytokine-cytokine receptor interaction - Homo sapiens (human)HIF-1 signaling pathway - Homo sapiens (human)Necroptosis - Homo sapiens (human)Osteoclast differentiation - Homo sapiens (human)JAK-STAT signaling pathway - Homo sapiens (human)Natural killer cell mediated cytotoxicity - Homo sapiens (human)Th1 and Th2 cell differentiation - Homo sapiens (human)Th17 cell differentiation - Homo sapiens (human)Leishmaniasis - Homo sapiens (human)Chagas disease - Homo sapiens (human)
via MyGene.info
Gene · Ensembl
interferon gamma receptor 1
- Symbol
- IFNGR1
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 6:137,197,483-137,219,449
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI