IL22
Sign in to saveAlso known as IL-21, IL-22, IL-D110, IL-TIF, ILTIF, TIFIL-23, TIFa, zcyto18
protein-coding gene in the species Homo sapiens
Gene data
IL22- Name
- interleukin 22
- Type
- protein-coding
- Position
- 68,248,242–68,253,604 (−)
- Aliases
- IL-21, IL-22, IL-D110, IL-TIF, ILTIF, TIFIL-23, TIFa, zcyto18
- Ensembl
- ENSG00000127318
- RefSeq RNA
- NM_020525.5
- RefSeq protein
- NP_065386.1
This gene is a member of the IL10 family of cytokines that mediate cellular inflammatory responses. The encoded protein functions in antimicrobial defense at mucosal surfaces and in tissue repair. This protein also has pro-inflammatory properties and plays a role in in the pathogenesis of several intestinal diseases. The encoded protein is a crucial cytokine that regulates host immunity in infectious diseases, including COVID-19 (disease caused by SARS-CoV-2). [provided by RefSeq, Dec 2021].
Gene Ontology
Biological process
Pathways
Cytokine-cytokine receptor interaction - Homo sapiens (human)JAK-STAT signaling pathway - Homo sapiens (human)Th17 cell differentiation - Homo sapiens (human)Inflammatory bowel disease - Homo sapiens (human)Cytokine Signaling in Immune systemDiseaseImmune SystemSignaling by InterleukinsDiseases of signal transduction by growth factor receptors and second messengersInterleukin-20 family signaling
via MyGene.info
Gene · Ensembl
interleukin 22
- Symbol
- IL22
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 12:68,248,242-68,253,604
- Strand
- Reverse (−)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI