IL17RD
Sign in to saveAlso known as HH18, IL-17RD, IL17RLM, SEF, interleukin 17 receptor D
Interleukin 17 receptor D (also known as Sef) is a protein that in humans is encoded by the IL17RD gene.
Gene data
IL17RD- Name
- interleukin 17 receptor D
- Type
- protein-coding
- Position
- 57,089,982–57,170,306 (−)
- Aliases
- HH18, IL-17RD, IL17RLM, SEF
- Ensembl
- ENSG00000144730
- RefSeq RNA
- NM_001318864.2, NM_017563.5, XM_005265238.5, XM_011533849.2, XM_047448369.1
- RefSeq protein
- NP_001305793.1, NP_060033.3, XP_005265295.1, XP_011532151.2, XP_047304325.1
This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin. The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling. Alternate splicing generates multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016].
Gene Ontology
Biological process
Pathways
via MyGene.info
Wikidata facts
Show 5 more facts
- HomoloGene ID
- 9717
- exact match
- identifiers.org/ncbigene/54756
- genomic end
- 57204334
- genomic start
- 57124010
- cytogenetic location
- 3p14.3
Sources (4)
via Wikidata · CC0
~5 min read
Article
9 sectionsContents
- Identification
- Structure
- IL-17RD in development
- IL-17RD in inflammation
- IL-17 signaling
- TLR signaling
- TNF signaling
- References
- Further reading
Interleukin 17 receptor D (also known as Sef) is a protein that in humans is encoded by the IL17RD gene.
This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. Alternate splicing generates multiple transcript variants encoding distinct isoforms. IL-17RD has been described to limit fibroblast growth factor receptor (FGFR) signaling and to be a part of the IL-17 receptor signaling complex.