Structure via PubChem · Public domain (PubChem)
iopamidol
Sign in to saveAlso known as Scanlux-300, Iopamidol-300, Isovue-M 300, Isovue-250, Isovue-128, Iopamidol-200, Isovue-370, Isovue-M 200
Iopamidol (INN), sold under the brand name Isovue among others, is a nonionic, low-osmolar iodinated contrast agent, developed by Bracco Diagnostics.
Chemical data
- Formula
- C17H22I3N3O8
- Molecular weight
- 777.1 g/mol
- IUPAC name
- 1-N,3-N-bis(1,3-dihydroxypropan-2-yl)-5-[[(2S)-2-hydroxypropanoyl]amino]-2,4,6-triiodobenzene-1,3-dicarboxamide
- SMILES
- C[C@@H](C(=O)NC1=C(C(=C(C(=C1I)C(=O)NC(CO)CO)I)C(=O)NC(CO)CO)I)O
- InChIKey
- XQZXYNRDCRIARQ-LURJTMIESA-N
- XLogP
- -2.4
- Polar surface area
- 188 Ų
- H-bond donors
- 8
- H-bond acceptors
- 8
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1985
- Admin. routes
- parenteral
- Indications
- renal cell carcinoma, urothelial carcinoma, prostate cancer, breast cancer
via ChEMBL · EBI
Research
3,476 papers- INTRAVENOUS IOPAMIDOL PHARMACOKINETICS IN COMMON CARP (CYPRINUS CARPIO).Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians · 2021
- [Iopamidol is a safe choice in the practice of diagnostic imaging].Vestnik rentgenologii i radiologii · 2011
- Nephrotoxicity of iopamidol is associated with mitochondrial impairment in human cell and teleost models.Toxicology and applied pharmacology · 2023
- Iopamidol myelography-induced seizures.MedGenMed : Medscape general medicine · 2005
- Iopamidol myelography in the horse.Equine veterinary journal · 1986
via PubMed
Wikidata facts
- Mass
- 776.854
- Has use
- medication
Show 7 more facts
- chemical formula
- C₁₇H₂₂I₃N₃O₈
- canonical SMILES
- CC(C(=O)NC1=C(C(=C(C(=C1I)C(=O)NC(CO)CO)I)C(=O)NC(CO)CO)I)O
- isomeric SMILES
- C[C@@H](C(=O)NC1=C(C(=C(C(=C1I)C(=O)NC(CO)CO)I)C(=O)NC(CO)CO)I)O
- World Health Organisation international non-proprietary name
- iopamidol
- subject has role
- contrast agent
- Commons category
- Iopamidol
- legal status (medicine)
- boxed warning
via Wikidata · CC0
~2 min read
Encyclopedic overview
2 sectionsContents
- Medical uses
- References
Iopamidol (INN), sold under the brand name Isovue among others, is a nonionic, low-osmolar iodinated contrast agent, developed by Bracco Diagnostics.
It is available in various concentrations, from 200 to 370 mgI/mL.
Excerpted from Wikipedia’s “iopamidol” article, available under the CC BY-SA 4.0 licence.
Available in 9 languages
via Wikidata sitelinks · CC0