KDM4C
Sign in to saveAlso known as lysine demethylase 4C, GASC1, JHDM3C, JMJD2C, TDRD14C, bA146B14.1
Lysine-specific demethylase 4C is an enzyme that in humans is encoded by the KDM4C gene.
In the Vinony graph
Vinony's link graph records 2 inbound references to KDM4C, and connects out to PubMed, human chromosome 9 and Ensembl genome database project.
It is catalogued under topics including EC 1.14.11, Genes mutated in mice and Genes on human chromosome 9.
Vinony links it to 5 Wikipedia language editions.
Gene data
KDM4C- Name
- lysine demethylase 4C
- Type
- protein-coding
- Position
- 6,720,863–7,175,648 (+)
- Aliases
- GASC1, JHDM3C, JMJD2C, TDRD14C
- Ensembl
- ENSG00000107077
- RefSeq RNA
- NM_001146694.1, NM_001146695.4, NM_001146696.2, NM_001304339.4, NM_001304340.4
- RefSeq protein
- NP_001140167.1, NP_001140168.1, NP_001291268.1, NP_001291269.1, NP_001291270.1
This gene is a member of the Jumonji domain 2 (JMJD2) family. The encoded protein is a trimethylation-specific demethylase, and converts specific trimethylated histone residues to the dimethylated form. This enzymatic action regulates gene expression and chromosome segregation. Chromosomal aberrations and changes in expression of this gene may be found in tumor cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015].
Gene Ontology
Biological process
Molecular function
Pathways
via MyGene.info
Gene · Ensembl
lysine demethylase 4C
- Symbol
- KDM4C
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 9:6,720,863-7,175,648
- Strand
- Forward (+)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein KDM4C PDB 2XDP.png
Show 8 more facts
- HomoloGene ID
- 41004
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/23081
- chromosome
- human chromosome 9
- genomic start
- 6720863
- genomic end
- 7175648
- cytogenetic location
- 9p24.1
- expressed in
- granulocyte
Sources (4)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- Function
- References
- Further reading
Lysine-specific demethylase 4C is an enzyme that in humans is encoded by the KDM4C gene.
== Function ==
Excerpted from Wikipedia’s “KDM4C” article, available under the CC BY-SA 4.0 licence.