KMT2C

Also known as HALR, MLL3, lysine methyltransferase 2C, KLEFS2

Lysine N-methyltransferase 2C (KMT2C) also known as myeloid/lymphoid or mixed-lineage leukemia protein 3 (MLL3) is an enzyme that in humans is encoded by the KMT2C gene.

Gene data

KMT2C

Name: lysine methyltransferase 2C
Type: protein-coding
Aliases: HALR, KLEFS2, MLL3

This gene is a member of the myeloid/lymphoid or mixed-lineage leukemia (MLL) family and encodes a nuclear protein with an AT hook DNA-binding domain, a DHHC-type zinc finger, six PHD-type zinc fingers, a SET domain, a post-SET domain and a RING-type zinc finger. This protein is a member of the ASC-2/NCOA6 complex (ASCOM), which possesses histone methylation activity and is involved in transcriptional coactivation. [provided by RefSeq, Jul 2008].

via MyGene.info

Wikidata facts

Image: Protein MLL3 PDB 2YSM.png

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HomoloGene ID: 46480
exact match: identifiers.org/ncbigene/58508
genomic end: 152436644
genomic start: 151832010
cytogenetic location: 7q36.1

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Contents

Function
Interactions
Clinical significance
References
Further reading
External links

Lysine N-methyltransferase 2C (KMT2C) also known as myeloid/lymphoid or mixed-lineage leukemia protein 3 (MLL3) is an enzyme that in humans is encoded by the KMT2C gene.

== Function ==