latamoxef

Also known as Oxa-cephem, LMOX, Lamoxactam, Latamoxefum, moxalactam, festamoxin

Latamoxef (or moxalactam) is an oxacephem antibiotic usually grouped with the cephalosporins. In oxacephems such as latamoxef, the sulfur atom of the cephalosporin core is replaced with an oxygen atom.

Chemical data

Formula: C20H20N6O9S
Molecular weight: 520.5 g/mol
IUPAC name: (6R,7R)-7-[[2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

via PubChem

Drug data · ChEMBL

Max clinical phase: Approved
Molecule type: Small molecule
First approval: 1982
Admin. routes: parenteral
Indications: bacterial disease

via ChEMBL · EBI

Research

1,803 papers

Latamoxef-induced coagulation disorders: Incidence and risk factors.Journal of clinical pharmacy and therapeutics · 2021
Latamoxef, alias moxalactam.Lancet (London, England) · 1983
Latamoxef and the newborn.Archives of disease in childhood · 1984
Latamoxef-associated hypoprothrombinaemia.Lancet (London, England) · 1983
Latamoxef-associated hypoprothrombinaemia.Lancet (London, England) · 1983

via PubMed

Wikidata facts

Mass: 520.101

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chemical formula: C₂₀H₂₀N₆O₉S
canonical SMILES: CN1C(=NN=N1)SCC2=C(N3C(C(C3=O)(NC(=O)C(C4=CC=C(C=C4)O)C(=O)O)OC)OC2)C(=O)O
isomeric SMILES: CN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@](C3=O)(NC(=O)C(C4=CC=C(C=C4)O)C(=O)O)OC)OC2)C(=O)O
World Health Organisation international non-proprietary name: latamoxef
defined daily dose: 4
Commons category: Latamoxef

Sources (5)

via Wikidata · CC0

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Article

2 sections

Contents

Synthesis
References

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