Structure via PubChem · Public domain (PubChem)
latamoxef
Sign in to saveAlso known as Oxa-cephem, LMOX, Lamoxactam, Latamoxefum, moxalactam, festamoxin
Latamoxef (or moxalactam) is an oxacephem antibiotic usually grouped with the cephalosporins. In oxacephems such as latamoxef, the sulfur atom of the cephalosporin core is replaced with an oxygen atom.
Chemical data
- Formula
- C20H20N6O9S
- Molecular weight
- 520.5 g/mol
- IUPAC name
- (6R,7R)-7-[[2-carboxy-2-(4-hydroxyphenyl)acetyl]amino]-7-methoxy-3-[(1-methyltetrazol-5-yl)sulfanylmethyl]-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1982
- Admin. routes
- parenteral
- Indications
- bacterial disease
via ChEMBL · EBI
Research
1,803 papers- Latamoxef-induced coagulation disorders: Incidence and risk factors.Journal of clinical pharmacy and therapeutics · 2021
- Latamoxef, alias moxalactam.Lancet (London, England) · 1983
- Latamoxef and the newborn.Archives of disease in childhood · 1984
- Latamoxef-associated hypoprothrombinaemia.Lancet (London, England) · 1983
- Latamoxef-associated hypoprothrombinaemia.Lancet (London, England) · 1983
via PubMed
Wikidata facts
- Subclass of
- carboxylic acid
- Mass
- 520.101
- Has use
- medication
Show 8 more facts
- chemical formula
- C₂₀H₂₀N₆O₉S
- canonical SMILES
- CN1C(=NN=N1)SCC2=C(N3C(C(C3=O)(NC(=O)C(C4=CC=C(C=C4)O)C(=O)O)OC)OC2)C(=O)O
- isomeric SMILES
- CN1C(=NN=N1)SCC2=C(N3[C@@H]([C@@](C3=O)(NC(=O)C(C4=CC=C(C=C4)O)C(=O)O)OC)OC2)C(=O)O
- World Health Organisation international non-proprietary name
- latamoxef
- defined daily dose
- 4
- subject has role
- bactericide
- medical condition treated
- bacterial infectious disease
- Commons category
- Latamoxef
via Wikidata · CC0
~4 min read
Encyclopedic overview
2 sectionsContents
- Synthesis
- References
{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 408571626 | IUPAC_name = (6R,7R)-7-{[carboxy(4-hydroxyphenyl)acetyl]amino}-7-methoxy-3-{[(1-methyl-1H-tetrazol-5-yl)thio]methyl}-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid | image = Latamoxef.svg | image_class = skin-invert-image
| tradename = | Drugs.com = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = Intramuscular, intravenous
Excerpted from Wikipedia’s “latamoxef” article, available under the CC BY-SA 4.0 licence.