LDB2
Sign in to saveAlso known as CLIM1, LDB1, LDB-2, LIM domain binding 2
LIM domain-binding protein 2 is a protein that in humans is encoded by the LDB2 gene.
In the Vinony graph
Within Vinony's link graph, LDB2 is referenced by 2 other articles, and connects out to PubMed, human chromosome 4 and Ensembl genome database project.
It is catalogued under the topic Genes on human chromosome 4.
Its subject is documented across 7 Wikipedia language editions.
Gene data
LDB2- Name
- LIM domain binding 2
- Type
- protein-coding
- Position
- 16,501,534–16,898,961 (−)
- Aliases
- CLIM1, LDB-2, LDB1
- Ensembl
- ENSG00000169744
- RefSeq RNA
- NM_001130834.3, NM_001290.5, NM_001304434.2, NM_001304435.2, NR_130734.2
- RefSeq protein
- NP_001124306.1, NP_001281.1, NP_001291363.1, NP_001291364.1, XP_005248254.1
The protein encoded by this gene belongs to the LIM-domain binding family. Members of this family are characterized by a conserved nuclear localization sequence, an amino-terminal homodimerization domain and a carboxy-terminal LIM interaction domain. These proteins function as adapter molecules to allow assembly of transcriptional regulatory complexes. Genetic association studies suggest functions for this gene in rhegmatogenous retinal detachment and coronary artery disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015].
Gene Ontology
Biological process
Molecular function
via MyGene.info
Gene · Ensembl
LIM domain binding 2
- Symbol
- LDB2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 4:16,501,534-16,898,961
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
Show 8 more facts
- HomoloGene ID
- 989
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/9079
- genomic end
- 16898678
- genomic start
- 16503164
- chromosome
- human chromosome 4
- cytogenetic location
- 4p15.32
- expressed in
- Achilles tendon
Sources (3)
via Wikidata · CC0
~1 min read
Encyclopedic overview
3 sectionsContents
- See also
- References
- Further reading
LIM domain-binding protein 2 is a protein that in humans is encoded by the LDB2 gene.
== See also == LIM domain LIM domain-binding protein family
Excerpted from Wikipedia’s “LDB2” article, available under the CC BY-SA 4.0 licence.