RCBTB2

Also known as CHC1L, RLG, RCC1 and BTB domain containing protein 2

RCC1 and BTB domain-containing protein 2 is a protein that in humans is encoded by the RCBTB2 gene.

In the Vinony graph

Vinony's link graph records 4 inbound references to RCBTB2, and connects out to PubMed, human chromosome 13 and Ensembl genome database project.

It is catalogued under the topic Genes on human chromosome 13.

Vinony links it to 6 Wikipedia language editions.

Gene data

RCBTB2

Name: RCC1 and BTB domain containing protein 2
Type: protein-coding
Position: 48,488,858–48,536,006 (−)
Aliases: CHC1L, RLG
Ensembl: ENSG00000136161
RefSeq RNA: NM_001268.4, NM_001286830.2, NM_001286831.2, NM_001286832.2, NM_001352424.2
RefSeq protein: NP_001259.1, NP_001273759.1, NP_001273760.1, NP_001273761.1, NP_001339353.1

This gene encodes a protein containing two C-terminal BTB/POZ domains that is related to regulator of chromosome condensation (RCC). The encoded protein may act as a guanine nucleotide exchange factor. This gene is observed to be lost or underexpressed in prostate cancers. There is a pseudogene of this gene on chromosome 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013].

Gene Ontology

Molecular function

guanyl-nucleotide exchange factor activity protein binding

Cellular component

acrosomal vesicle cytoplasm

via MyGene.info

Gene · Ensembl

RCC1 and BTB domain containing protein 2

Symbol: RCBTB2
Biotype: Protein coding
Organism: Homo sapiens
Location: 13:48,488,858-48,536,006
Strand: Reverse (−)
Assembly: GRCh38

View on Ensembl →

via Ensembl · EMBL-EBI

Wikidata facts

Instance of: gene

Show 7 more facts

HomoloGene ID: 970
found in taxon: Homo sapiens
exact match: identifiers.org/ncbigene/1102
genomic end: 49107369
genomic start: 48488963
chromosome: human chromosome 13
cytogenetic location: 13q14.2

Sources (4)

via Wikidata · CC0

~1 min read

Encyclopedic overview

2 sections

Contents

References
Further reading

RCC1 and BTB domain-containing protein 2 is a protein that in humans is encoded by the RCBTB2 gene.

This gene encodes a member of the RCC1-related GEF family. The N-terminal half of the encoded amino acid sequence shows similarity to the regulator of chromosome condensation RCC1, which acts as a guanine nucleotide exchange factor (GEF) protein for the Ras-related GTPase Ran.

Excerpted from Wikipedia’s “RCBTB2” article, available under the CC BY-SA 4.0 licence.