LMAN2L

Name

lectin, mannose binding 2 like

Type

protein-coding

Position

96,704,824–96,740,087 (−)

Aliases

MRD69, MRT52, VIPL

Ensembl

ENSG00000114988

RefSeq RNA

NM_001142292.2, NM_001322346.2, NM_001322347.2, NM_001322350.2, NM_001322351.2

RefSeq protein

NP_001135764.1, NP_001309275.1, NP_001309276.1, NP_001309279.1, NP_001309280.1

This gene encodes a protein belonging to the L-type lectin group of type 1 membrane proteins, which function in the mammalian early secretory pathway. These proteins contain luminal carbohydrate recognition domains, which display homology to leguminous lectins. Unlike other proteins of the group, which cycle in the early secretory pathway and are predominantly associated with post endoplasmic reticulum membranes, the protein encoded by this gene is a non-cycling resident protein of the ER, where it functions as a cargo receptor for glycoproteins. It is proposed to regulate exchange of folded proteins for transport to the Golgi and exchange of misfolded glycoproteins for transport to the ubiquitin-proteasome pathway. [provided by RefSeq, Apr 2016].

via MyGene.info

Gene · Ensembl

lectin, mannose binding 2 like

Symbol

LMAN2L

Biotype

Protein coding

Organism

Homo sapiens

Location

2:96,704,824-96,740,087

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

via Wikidata · CC0