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EntityQ6459673· pop 5· linked from 785 articles

'''N-Pyrrolidyllysergamide (LPD-824), also known as lysergic acid pyrrolidide (LA-Pyr'), is a psychedelic drug of the lysergamide family related to lysergic acid diethylamide (LSD). It is the analogue of LSD in which the N,N-diethylamide moiety has been cyclized into an N,N''-pyrrolidide ring.

Wikidata facts

Mass
321.184112
Show 3 more facts
chemical formula
C₂₀H₂₃N₃O
canonical SMILES
CN1CC(C=C2C1CC3=CNC4=CC=CC2=C34)C(=O)N5CCCC5
isomeric SMILES
CN1C[C@@H](C=C2[C@H]1CC3=CNC4=CC=CC2=C34)C(=O)N5CCCC5
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  • Use and effects
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  • Pharmacology
  • Pharmacodynamics
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'''N-Pyrrolidyllysergamide (LPD-824), also known as lysergic acid pyrrolidide (LA-Pyr'), is a psychedelic drug of the lysergamide family related to lysergic acid diethylamide (LSD). It is the analogue of LSD in which the N,N-diethylamide moiety has been cyclized into an N,N''-pyrrolidide ring.

==Use and effects== The drug has been reported to have mild and relatively short-lasting LSD-like effects in humans at an oral dose of 800μg equivalent to one-tenth this amount of LSD (i.e., 80μg). Based on different clinical studies, it is estimated to be 5 to 10% as potent as LSD in humans. Its duration was shorter than that of LSD, lasting around 5hours as opposed to 7hours in the case of LSD. The drug produced nausea at small doses in humans, which was dose-limiting in terms of evaluating its effects.

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