Structure via PubChem · Public domain (PubChem)
α-methyl-5-HT
Sign in to saveAlso known as α-Me-5-HT, alpha-methyl-5-HT, alpha-methyl-5-hydroxytryptamine, α-methylserotonin
α-Methylserotonin (αMS), also known as α-methyl-5-hydroxytryptamine (α-methyl-5-HT) or as 5-hydroxy-α-methyltryptamine (5-HO-αMT), is a tryptamine derivative closely related to the neurotransmitter serotonin (5-HT). It acts as a non-selective serotonin receptor agonist and has been used extensively in scientific research to study the function of the serotonin system.
Chemical data
- Formula
- C11H14N2O
- Molecular weight
- 190.24 g/mol
- IUPAC name
- 3-(2-aminopropyl)-1H-indol-5-ol
- SMILES
- CC(CC1=CNC2=C1C=C(C=C2)O)N
- InChIKey
- LYPCGXKCQDYTFV-UHFFFAOYSA-N
- XLogP
- 0.6
- Polar surface area
- 62 Ų
- H-bond donors
- 3
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Mass
- 190.110613
Show 3 more facts
- chemical formula
- C₁₁H₁₄N₂O
- canonical SMILES
- CC(CC1=CNC2=C1C=C(C=C2)O)N
- Commons category
- 5-HO-AMT
Sources (2)
via Wikidata · CC0
~4 min read
Encyclopedic overview
15 sectionsContents
- Use and effects
- Pharmacology
- Pharmacodynamics
- Pharmacokinetics
- Chemistry
- Properties
- Analogues
- Society and culture
- Legal status
- Canada
- United States
- Florida
- See also
- References
- External links
α-Methylserotonin (αMS), also known as α-methyl-5-hydroxytryptamine (α-methyl-5-HT) or as 5-hydroxy-α-methyltryptamine (5-HO-αMT), is a tryptamine derivative closely related to the neurotransmitter serotonin (5-HT). It acts as a non-selective serotonin receptor agonist and has been used extensively in scientific research to study the function of the serotonin system.
==Use and effects== According to Alexander Shulgin in his book TiHKAL (Tryptamines I Have Known and Loved), αMS is well-studied in preclinical research but has not been tested in humans.
Excerpted from Wikipedia’s “α-methyl-5-HT” article, available under the CC BY-SA 4.0 licence.