LTC4S

Name

leukotriene C4 synthase

Type

protein-coding

The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family includes a number of human proteins, several of which are involved the production of leukotrienes. This gene encodes an enzyme that catalyzes the first step in the biosynthesis of cysteinyl leukotrienes, potent biological compounds derived from arachidonic acid. Leukotrienes have been implicated as mediators of anaphylaxis and inflammatory conditions such as human bronchial asthma. This protein localizes to the nuclear envelope and adjacent endoplasmic reticulum. [provided by RefSeq, Jul 2008].

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Gene · Ensembl

leukotriene C4 synthase

Symbol

LTC4S

Biotype

Protein coding

Organism

Homo sapiens

Location

Chr HG30_PATCH:559,557-562,224

Strand

Forward (+)

Assembly

GRCh38