Structure via PubChem · Public domain (PubChem)
luliconazole
Sign in to saveAlso known as Lulicon®, Luzu®, NND-502, PR-2699
Luliconazole, trade names Luzu among others, is an imidazole antifungal medication. As a 1% topical cream, It is indicated for the treatment of athlete's foot, jock itch, and ringworm caused by dermatophytes such as Trichophyton rubrum, Microsporum gypseum, and Epidermophyton floccosum.
Key facts
- Drug.IUPAC_name
- (2E)-[(4R)-4-(2,4-Dichlorophenyl)-1,3-dithiolan-2-ylidene](1H-imidazol-1-yl)acetonitrile
- Drug.image
- Luliconazole.svg
- Drug.image_class
- skin-invert-image
- Drug.image2
- Luliconazole ball-and-stick model.png
- Drug.image_class2
- bg-transparent
- Drug.tradename
- Luzu, Luzarn, Lulicon, LULY, Zyluli,Luris
- Drug.legal_status
- Rx-only
- Drug.routes_of_administration
- Topical
- Drug.protein_bound
- >99%
- Drug.ATC_prefix
- D01
- Drug.ATC_suffix
- AC18
- Drug.DrugBank
- DB08933
- Drug.CAS_number
- 187164-19-8
- Drug.UNII
- RE91AN4S8G
- Drug.PubChem
- 3003141
- Drug.ChemSpiderID
- 2273807
- Drug.smiles
- C1[C@H](S/C(=C(\C#N)/N2C=CN=C2)/S1)C3=C(C=C(C=C3)Cl)Cl
- Drug.StdInChI
- 1S/C14H9Cl2N3S2/c15-9-1-2-10(11(16)5-9)13-7-20-14(21-13)12(6-17)19-4-3-18-8-19/h1-5,8,13H,7H2/b14-12+/t13-/m0/s1
via Wikipedia infobox
Chemical data
- Formula
- C14H9Cl2N3S2
- Molecular weight
- 354.3 g/mol
- IUPAC name
- (2E)-2-[(4R)-4-(2,4-dichlorophenyl)-1,3-dithiolan-2-ylidene]-2-imidazol-1-ylacetonitrile
- SMILES
- C1[C@H](S/C(=C(\C#N)/N2C=CN=C2)/S1)C3=C(C=C(C=C3)Cl)Cl
- InChIKey
- YTAOBBFIOAEMLL-REQDGWNSSA-N
- XLogP
- 4
- Polar surface area
- 92.2 Ų
- H-bond donors
- 0
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 2013
- Admin. routes
- topical
- Indications
- tinea, tinea pedis, tinea unguium
via ChEMBL · EBI
Wikidata facts
- Subclass of
- azole
- Mass
- 352.961
- Has use
- medication
Show 5 more facts
- Commons category
- Luliconazole
- chemical formula
- C₁₄H₉Cl₂N₃S₂
- isomeric SMILES
- C1[C@H](S/C(=C(\C#N)/N2C=CN=C2)/S1)C3=C(C=C(C=C3)Cl)Cl
- canonical SMILES
- C1C(SC(=C(C#N)N2C=CN=C2)S1)C3=C(C=C(C=C3)Cl)Cl
- medical condition treated
- tinea cruris
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- References
- External links
Luliconazole, trade names Luzu among others, is an imidazole antifungal medication. As a 1% topical cream, It is indicated for the treatment of athlete's foot, jock itch, and ringworm caused by dermatophytes such as Trichophyton rubrum, Microsporum gypseum, and Epidermophyton floccosum.
==References==
Excerpted from Wikipedia’s “luliconazole” article, available under the CC BY-SA 4.0 licence.