fenticonazole
Sign in to saveFenticonazole is an imidazole antifungal drug, used locally as the nitrate in the treatment of vulvovaginal candidiasis. It is active against a range of organisms including Trichophyton mentagrophytes, Malassezia furfur, and Candida albicans. Fenticonazole has also been shown to exhibit antibacterial action, with a spectrum of activity that includes bacteria commonly associated with superinfected fungal skin and vaginal infections, and antiparasitic action against the protozoan Trichomonas vaginalis.
Research
105 papers- Topical fenticonazole in dermatology and gynaecology: current role in therapy.Drugs · 2008
- Fenticonazole: an effective topical treatment for superficial mycoses as the first-step of antifungal stewardship program.European review for medical and pharmacological sciences · 2017
- Therapeutic effects of fenticonazole on bacterial vaginosis in mice.FEMS microbiology letters · 2023
- Repurposing fenticonazole nitrate to restore colistin susceptibility in multidrug-resistant bacteria.Life sciences · 2025
- DETERMINATION OF THE SENSITIVITY OF GARDNERELLA VAGINALIS TO FENTICONAZOLE.Georgian medical news · 2022
via PubMed
Wikidata facts
- Mass
- 454.067
Show 3 more facts
- chemical formula
- C₂₄H₂₀Cl₂N₂OS
- canonical SMILES
- C1=CC=C(C=C1)SC2=CC=C(C=C2)COC(CN3C=CN=C3)C4=C(C=C(C=C4)Cl)Cl
- Commons category
- Fenticonazole
Sources (2)
via Wikidata · CC0
~3 min read
Article
6 sectionsContents
- Uses and administration
- Pregnancy and lactation
- Adverse effects
- See also
- References
- Further reading
{{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 447916794 | IUPAC_name = 1-[2-(2,4-dichlorophenyl)-2-{[4-(phenylsulfanyl)phenyl]methoxy}ethyl]-1H-imidazole | image = Fenticonazole.svg | image_class = skin-invert-image | width = 250
| tradename = Lomexin, Gynoxin | Drugs.com = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = POM | legal_US = Not approved | legal_status = Rx-only | routes_of_administration = Topical (ovule, spray, cream)