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abafungin
Sign in to saveAbafungin (INN) is a broad-spectrum arylguanidines-class antifungal agent with a novel mechanism of action for the treatment of dermatomycoses.
Chemical data
- Formula
- C21H22N4OS
- Molecular weight
- 378.5 g/mol
- IUPAC name
- 4-[2-(2,4-dimethylphenoxy)phenyl]-N-(1,4,5,6-tetrahydropyrimidin-2-yl)-1,3-thiazol-2-amine
- SMILES
- CC1=CC(=C(C=C1)OC2=CC=CC=C2C3=CSC(=N3)NC4=NCCCN4)C
- InChIKey
- TYBHXIFFPVFXQW-UHFFFAOYSA-N
- XLogP
- 4.3
- Polar surface area
- 86.8 Ų
- H-bond donors
- 2
- H-bond acceptors
- 4
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 378.151432
Show 4 more facts
- chemical formula
- C₂₁H₂₂N₄OS
- canonical SMILES
- CC1=CC(=C(C=C1)OC2=CC=CC=C2C3=CSC(=N3)NC4=NCCCN4)C
- World Health Organisation international non-proprietary name
- abafungin
- Commons category
- Abafungin
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
4 sectionsContents
- History
- Mechanism of action
- References
- External links
Abafungin (INN) is a broad-spectrum arylguanidines-class antifungal agent with a novel mechanism of action for the treatment of dermatomycoses.
Abasol is a topical cream formulation of abafungin by York Pharma.
Excerpted from Wikipedia’s “abafungin” article, available under the CC BY-SA 4.0 licence.