mafenide
Sign in to saveAlso known as Sulfamylon, 4-Homosufanilamide, Maphenidum, Bensulfamide, 4-(aminomethyl)benzenesulfonamide
Mafenide (INN; usually as mafenide acetate, trade name Sulfamylon) is a sulfonamide-type medication used as an antibiotic. It was approved by the FDA in 1948.
Research
291 papers- Mafenide acetate cream: a review.Drugs · 1971
- Topical mafenide hydrochloride aqueous spray in initial management of massive contaminated wounds with devitalized tissue.Prehospital and disaster medicine · 2001
- Mafenide derivatives inhibit neuroinflammation in Alzheimer's disease by regulating pyroptosis.Journal of cellular and molecular medicine · 2021
- Mafenide-induced pseudochondritis.The Journal of burn care & rehabilitation · 1988
- The mafenide story.The British journal of dermatology · 1973
via PubMed
Wikidata facts
- Mass
- 186.046299
- Has use
- medication
Show 4 more facts
- chemical formula
- C₇H₁₀N₂O₂S
- medical condition treated
- bacterial infectious disease
- canonical SMILES
- C1=CC(=CC=C1CN)S(=O)(=O)N
- Commons category
- Mafenide
Sources (2)
via Wikidata · CC0
~2 min read
Encyclopedic overview
8 sectionsContents
- Uses
- Mechanism of action
- Adverse reactions
- Drug interactions
- Contraindications
- Dosage
- References
- External links
Mafenide (INN; usually as mafenide acetate, trade name Sulfamylon) is a sulfonamide-type medication used as an antibiotic. It was approved by the FDA in 1948.
==Uses== Mafenide is used to treat severe burns. It is used topically as an adjunctive therapy for second- and third-degree burns. It is bacteriostatic against many gram-positive and gram-negative organisms, including Pseudomonas aeruginosa. Some sources state that mafenide is more appropriate for non-facial burns, while chloramphenicol/prednisolone or bacitracin are more appropriate for facial burns.
Excerpted from Wikipedia’s “mafenide” article, available under the CC BY-SA 4.0 licence.