MAP2K6

Name

mitogen-activated protein kinase kinase 6

Type

protein-coding

Position

69,414,683–69,553,865 (+)

Aliases

CRCMSL, MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3

Ensembl

ENSG00000108984

RefSeq RNA

NM_001330450.2, NM_002758.4, NM_031988.1, XM_005257516.3, XM_006721975.4

RefSeq protein

NP_001317379.1, NP_002749.2, XP_005257573.1, XP_006722038.1, XP_011523329.1

This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

mitogen-activated protein kinase kinase 6

Symbol

MAP2K6

Biotype

Protein coding

Organism

Homo sapiens

Location

17:69,414,683-69,553,865

Strand

Forward (+)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein MAP2K6 PDB 3ENM.png

via Wikidata · CC0