MAP3K2

Name

mitogen-activated protein kinase kinase kinase 2

Type

protein-coding

Position

127,298,668–127,388,465 (−)

Aliases

MEKK2, MEKK2B

Ensembl

ENSG00000169967

RefSeq RNA

NM_001371910.2, NM_001371911.1, NM_006609.5, XM_047442989.1, XM_047442990.1

RefSeq protein

NP_001358839.1, NP_001358840.1, NP_006600.3, XP_047298945.1, XP_047298946.1

The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

mitogen-activated protein kinase kinase kinase 2

Symbol

MAP3K2

Biotype

Protein coding

Organism

Homo sapiens

Location

2:127,298,668-127,388,465

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

Image

Protein MAP3K2 PDB 2cu1.png

via Wikidata · CC0