MAP3K2
Sign in to saveAlso known as MEKK2, MEKK2B, mitogen-activated protein kinase kinase kinase 2
gen van de soort Homo sapiens
In the Vinony graph
Vinony's link graph records 304 inbound references to MAP3K2, and connects out to protein-serine-threonine kinases, PubMed and human chromosome 2.
It is catalogued under topics including EC 2.7.11, Genes on human chromosome 2 and Long stubs with short prose.
Vinony links it to 5 Wikipedia language editions.
Gene data
MAP3K2- Name
- mitogen-activated protein kinase kinase kinase 2
- Type
- protein-coding
- Position
- 127,298,668–127,388,465 (−)
- Aliases
- MEKK2, MEKK2B
- Ensembl
- ENSG00000169967
- RefSeq RNA
- NM_001371910.2, NM_001371911.1, NM_006609.5, XM_047442989.1, XM_047442990.1
- RefSeq protein
- NP_001358839.1, NP_001358840.1, NP_006600.3, XP_047298945.1, XP_047298946.1
The protein encoded by this gene is a member of serine/threonine protein kinase family. This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway. This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway. This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process. [provided by RefSeq, Jul 2008].
Gene Ontology
Biological process
Molecular function
Cellular component
Pathways
via MyGene.info
Gene · Ensembl
mitogen-activated protein kinase kinase kinase 2
- Symbol
- MAP3K2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 2:127,298,668-127,388,465
- Strand
- Reverse (−)
- Assembly
- GRCh38
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- gene
- Image
- Protein MAP3K2 PDB 2cu1.png
Show 8 more facts
- HomoloGene ID
- 74576
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/10746
- genomic end
- 128146041
- genomic start
- 127298668
- chromosome
- human chromosome 2
- cytogenetic location
- 2q14.3
- expressed in
- pylorus
Sources (4)
via Wikidata · CC0