MAPK3

Name

mitogen-activated protein kinase 3

Type

protein-coding

Position

30,114,104–30,123,506 (−)

Aliases

ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK

Ensembl

ENSG00000102882

RefSeq RNA

NM_001040056.3, NM_001109891.2, NM_002746.3, XR_008484707.1, XR_243293.2

RefSeq protein

NP_001035145.1, NP_001103361.1, NP_002737.2

The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described. [provided by RefSeq, Jul 2008].

via MyGene.info

Gene · Ensembl

mitogen-activated protein kinase 3

Symbol

MAPK3

Biotype

Protein coding

Organism

Homo sapiens

Location

16:30,114,104-30,123,506

Strand

Reverse (−)

Assembly

GRCh38

Wikidata facts

Instance of

gene

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