MAVS
Sign in to saveAlso known as CARDIF, IPS-1, IPS1, VISA, mitochondrial antiviral signaling protein
protein-coding gene in the species Homo sapiens
Gene data
MAVS- Name
- mitochondrial antiviral signaling protein
- Type
- protein-coding
- Position
- 3,842,694–3,876,123 (+)
- Aliases
- CARDIF, IPS-1, IPS1, VISA
- Ensembl
- ENSG00000088888
- RefSeq RNA
- NM_001206491.2, NM_001385663.1, NM_020746.5, NR_037921.2
- RefSeq protein
- NP_001193420.1, NP_001372592.1, NP_065797.2
This gene encodes an intermediary protein necessary in the virus-triggered beta interferon signaling pathways. It is required for activation of transcription factors which regulate expression of beta interferon and contributes to antiviral innate immunity. [provided by RefSeq, Jul 2020].
Gene Ontology
Biological process
activation of innate immune responsepositive regulation of defense response to virus by hostpositive regulation of defense response to virus by hostpositive regulation of defense response to virus by hostpositive regulation of myeloid dendritic cell cytokine productioncytoplasmic pattern recognition receptor signaling pathwaycytoplasmic pattern recognition receptor signaling pathwaysignal transduction
Molecular function
Pathways
NOD-like receptor signaling pathway - Homo sapiens (human)RIG-I-like receptor signaling pathway - Homo sapiens (human)Cytosolic DNA-sensing pathway - Homo sapiens (human)Hepatitis C - Homo sapiens (human)Hepatitis B - Homo sapiens (human)Measles - Homo sapiens (human)Influenza A - Homo sapiens (human)Herpes simplex virus 1 infection - Homo sapiens (human)Epstein-Barr virus infection - Homo sapiens (human)Coronavirus disease - COVID-19 - Homo sapiens (human)
via MyGene.info
Gene · Ensembl
mitochondrial antiviral signaling protein
- Symbol
- MAVS
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 20:3,842,694-3,876,123
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI
Wikidata facts
- Instance of
- protein
- Part of
- mitochondrion
Show 8 more facts
- HomoloGene ID
- 17004
- found in taxon
- Homo sapiens
- exact match
- identifiers.org/ncbigene/57506
- genomic end
- 3849280
- genomic start
- 3827487
- chromosome
- human chromosome 20
- cytogenetic location
- 20p13
- expressed in
- jejunum
Sources (4)
via Wikidata · CC0