Structure via PubChem · Public domain (PubChem)
methiopropamine
Sign in to saveMethiopropamine (MPA), also known as '''N-methylthiopropamine''', is an organic compound structurally related to methamphetamine. Originally reported in 1942, the molecule consists of a thiophene group with an alkyl amine substituent at the 2-position. It appeared for public sale in the United Kingdom in December 2010 as a "research chemical" or "legal high", recently branded as Blow. It has limited popularity as a recreational stimulant.
Chemical data
- Formula
- C8H13NS
- Molecular weight
- 155.26 g/mol
- IUPAC name
- N-methyl-1-thiophen-2-ylpropan-2-amine
- SMILES
- CC(CC1=CC=CS1)NC
- InChIKey
- HPHUWHKFQXTZPS-UHFFFAOYSA-N
- XLogP
- 1.9
- Polar surface area
- 40.3 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 155.077
Show 3 more facts
- chemical formula
- C₈H₁₃NS
- canonical SMILES
- CC(CC1=CC=CS1)NC
- Commons category
- Methiopropamine
Sources (2)
via Wikidata · CC0
~5 min read
Encyclopedic overview
14 sectionsContents
- Pharmacology
- Metabolism
- Synthesis
- Legal status
- China
- Finland
- Germany
- United Kingdom
- United States
- Florida
- Tasmania (Australia)
- See also
- References
- External links
Methiopropamine (MPA), also known as '''N-methylthiopropamine', is an organic compound structurally related to methamphetamine. Originally reported in 1942, the molecule consists of a thiophene group with an alkyl amine substituent at the 2-position. It appeared for public sale in the United Kingdom in December 2010 as a "research chemical" or "legal high", recently branded as Blow. It has limited popularity as a recreational stimulant.
==Pharmacology== Methiopropamine functions as a norepinephrine–dopamine reuptake inhibitor (NDRI) that is approximately 1.85 times more selective for norepinephrine than dopamine. It is approximately one-third as potent as dextroamphetamine as a norepinephrine reuptake inhibitor and one-fifth as much as a dopamine reuptake inhibitor. It displays negligible activity as a serotonin reuptake inhibitor.
Excerpted from Wikipedia’s “methiopropamine” article, available under the CC BY-SA 4.0 licence.