Structure via PubChem · Public domain (PubChem)
tandamine
Sign in to saveTandamine is a selective norepinephrine reuptake inhibitor with a tricyclic structure. It was developed in the 1970s as an antidepressant but was never commercialized. Tandamine is analogous to pirandamine, which, instead, acts as a selective serotonin reuptake inhibitor (SSRI).
Chemical data
- Formula
- C18H26N2S
- Molecular weight
- 302.5 g/mol
- IUPAC name
- 2-(9-ethyl-1-methyl-3,4-dihydrothiopyrano[3,4-b]indol-1-yl)-N,N-dimethylethanamine
- SMILES
- CCN1C2=CC=CC=C2C3=C1C(SCC3)(C)CCN(C)C
- InChIKey
- BRPOADLGOFPKKJ-UHFFFAOYSA-N
- XLogP
- 3.4
- Polar surface area
- 33.5 Ų
- H-bond donors
- 0
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Phase 2
- Molecule type
- Small molecule
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 302.18167
Show 2 more facts
- chemical formula
- C₁₈H₂₆N₂S
- canonical SMILES
- CCN1C2=CC=CC=C2C3=C1C(SCC3)(C)CCN(C)C
Sources (2)
via Wikidata · CC0
~1 min read
Encyclopedic overview
2 sectionsContents
- See also
- References
Tandamine is a selective norepinephrine reuptake inhibitor with a tricyclic structure. It was developed in the 1970s as an antidepressant but was never commercialized. Tandamine is analogous to pirandamine, which, instead, acts as a selective serotonin reuptake inhibitor (SSRI).
The exact identical same structure, although this time changing the thioether to a methylene group revealed a strongest compound of the series called AY 24614. == See also == Pirandamine
Excerpted from Wikipedia’s “tandamine” article, available under the CC BY-SA 4.0 licence.