甲基己胺

Also known as 4-methylhexan-2-amine, methylhexamine, 1,3-dimethylamylamine, dimethylamylamine

Methylhexanamine (also known as methylhexamine, 1,3-dimethylamylamine, 1,3-DMAA, dimethylamylamine, and DMAA; trade names Forthane and Geranamine) is an indirect sympathomimetic drug invented and developed by Eli Lilly and Company and marketed as an inhaled nasal decongestant from 1948 until it was voluntarily withdrawn from the market in the 1980s.

Key facts

Drug.Verifiedfields: changed
Drug.Watchedfields: changed
Drug.IUPAC_name: 4-Methylhexan-2-amine
Drug.image: Geranamine.svg
Drug.image_class: skin-invert-image
Drug.image2: Geranamine-3D-balls.png
Drug.image_class2: bg-transparent
Drug.legal_AU: S10
Drug.legal_BR: F2
Drug.legal_US: Unapproved drug; use in dietary supplements, food, or medicine is unlawful.
Drug.routes_of_administration: Nasal spray, oral
Drug.elimination_half life: ~8.5 hours
Drug.CAS_number: 105-41-9
Drug.UNII: X49C572YQO
Drug.ATC_prefix: None
Drug.PubChem: 7753
Drug.ChemSpiderID: 7467
Drug.C: 7

via Wikipedia infobox

Chemical data

Formula: C7H17N
Molecular weight: 115.22 g/mol
IUPAC name: 4-methylhexan-2-amine
SMILES: CCC(C)CC(C)N
InChIKey: YAHRDLICUYEDAU-UHFFFAOYSA-N
XLogP: 1.9
Polar surface area: 26 Å²
H-bond donors: 1
H-bond acceptors: 1
Formal charge: 0

via PubChem

Article · 中文

甲基己胺（又称1,3-二甲基戊胺、1,3-DMAA、二甲基戊胺和DMAA；商品名Forthane和Geranamine）是一种由礼来公司发明并研发的间接拟交感神经药，自1948年以来作为一种吸入型投放市场，但于1970年代被停止销售。自2006年以来，甲基己胺以许多名称作为兴奋剂或提高能量的补剂广泛销售，据说是因为它类似于老鹳草中的某些化合物，但因具有数个不良副作用而受到质疑，至少有五个死亡与含甲基己胺的补剂有关。它被许多运动管理局和政府机构禁止。即使FDA已发出几封警告信，截至2019年，这种化合物仍出现于运动和减肥补剂中。

Abstract from DBpedia / Wikipedia · CC BY-SA

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