Structure via PubChem · Public domain (PubChem)
methyprylon
Sign in to saveAlso known as methyprylone, methprylon, metiprilon, methyprolon
Methyprylon, or Noludar, is a sedative/tranquilizer and hypnotic central nervous system depressant of the piperidinedione derivative chemical class, first developed in the 1940s by Hoffmann-La Roche. This medicine was used for treating insomnia, but is now rarely used as it has been replaced by newer drugs with fewer side effects, such as benzodiazepines.
In the Vinony graph
Within Vinony's link graph, methyprylon is referenced by 600 other articles, and connects out to benzodiazepine drug, isovaleric acid and allopregnanolone.
It is catalogued under topics including 2-Piperidinones, 4-Piperidinones and Drugboxes which contain changes to verified fields.
Its subject is documented across 14 Wikipedia language editions.
Chemical data
- Formula
- C10H17NO2
- Molecular weight
- 183.25 g/mol
- IUPAC name
- 3,3-diethyl-5-methylpiperidine-2,4-dione
- SMILES
- CCC1(C(=O)C(CNC1=O)C)CC
- InChIKey
- SIDLZWOQUZRBRU-UHFFFAOYSA-N
- XLogP
- 0.8
- Polar surface area
- 46.2 Ų
- H-bond donors
- 1
- H-bond acceptors
- 2
- Formal charge
- 0
via PubChem
Drug data · ChEMBL
- Max clinical phase
- Approved
- Molecule type
- Small molecule
- First approval
- 1982
- Admin. routes
- oral
via ChEMBL · EBI
Wikidata facts
- Subclass of
- chemical compound
- Mass
- 183.125929
- Has use
- medication
Show 6 more facts
- chemical formula
- C₁₀H₁₇NO₂
- has characteristic
- bitterness
- medical condition treated
- insomnia
- canonical SMILES
- CCC1(C(=O)C(CNC1=O)C)CC
- defined daily dose
- 0.2
- Commons category
- Methyprylon
Sources (3)
via Wikidata · CC0
~2 min read
Encyclopedic overview
4 sectionsContents
- Adverse effects
- Pharmacokinetics
- See also
- References
Methyprylon, or Noludar, is a sedative/tranquilizer and hypnotic central nervous system depressant of the piperidinedione derivative chemical class, first developed in the 1940s by Hoffmann-La Roche. This medicine was used for treating insomnia, but is now rarely used as it has been replaced by newer drugs with fewer side effects, such as benzodiazepines.
Methyprylon was withdrawn from the US market in June 1975 and the Canadian market in September 1990. Some other trade names are Noctan and Dimerin.
Excerpted from Wikipedia’s “methyprylon” article, available under the CC BY-SA 4.0 licence.