MGAT1
Sign in to saveAlso known as GLCNAC-TI, GLCT1, GLYT1, GNT-1, GNT-I, MGAT, GnTI, mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase is an enzyme that in humans is encoded by the MGAT1 gene.
Gene data
MGAT1- Name
- alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
- Type
- protein-coding
- Aliases
- GLCNAC-TI, GLCT1, GLYT1, GNT-1, GNT-I, GnTI, MGAT
There are believed to be over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis. Several variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].
via MyGene.info
Wikidata facts
- Image
- Protein MGAT1 PDB 1fo8.png
Show 5 more facts
- HomoloGene ID
- 1804
- exact match
- identifiers.org/ncbigene/4245
- genomic end
- 180242652
- genomic start
- 180217541
- cytogenetic location
- 5q35.3
Sources (3)
via Wikidata · CC0
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Article
2 sectionsContents
- References
- Further reading
Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase is an enzyme that in humans is encoded by the MGAT1 gene.
There are over 100 different glycosyltransferases involved in the synthesis of protein-bound and lipid-bound oligosaccharides. UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I is a medial-Golgi enzyme essential for the synthesis of hybrid and complex N-glycans. The protein, encoded by a single exon, shows typical features of a type II transmembrane protein. The protein is believed to be essential for normal embryogenesis.