EntityQ3858659· pop 8· linked from 112 articles

midecamycin acetate

Miocamycin is a macrolide antibiotic. It has a spectrum activity similar to that of Erythromycin, but shows higher antimicrobial effect against certain bacteria including Legionella pneumophila (the causative agent of Legionnaires' Disease), Mycoplasma hominis, and Ureaplasma urealyticum. In-vivo studies have further expounded on Miocamycin's efficacy, reporting that the medication is more effective than in-vitro data suggests.

Chemical data

Formula: C45H71NO17
Molecular weight: 898 g/mol
IUPAC name: [(4R,5S,7R,9R,10R,11E,13E,16R)-10-acetyloxy-6-[(2S,3R,4R,5S,6R)-5-[(2S,4R,5S,6S)-4-acetyloxy-4,6-dimethyl-5-propanoyloxyoxan-2-yl]oxy-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-1-oxacyclohexadeca-11,13-dien-4-yl] propanoate

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Research

242 papers

[Diagnosis and treatment of acute tonsillopharyngitis. Consensus document update].Anales de pediatria · 2020
Macrolides allergy.Current pharmaceutical design · 2008
Bacteriological evaluation of midecamycin acetate and its metabolites.The Japanese journal of antibiotics · 1982
Midecamycin Is Inactivated by Several Different Sugar Moieties at Its Inactivation Site.International journal of molecular sciences · 2021
Effect of midecamycin acetate on gastrointestinal motility in humans.International journal of clinical pharmacology research · 1992

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Wikidata facts

Subclass of: chemical compound
Mass: +897.472

Show 1 more fact

P2868: antibiotic

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Article

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Contents

References

{{Drugbox | verifiedrevid = 444015174 | IUPAC_name = (2S,3S,4R,6S)-6-{[(2R,3S,4R,5R,6S)-6-{[(4S,5R,6S,7R,9R,10R,11E,13E,16R)-10-(acetyloxy)-5-methoxy-9,16-dimethyl-2-oxo-7-(2-oxoethyl)-4-propoxy-1-oxacyclohexadeca-11,13-dien-6-yl]oxy}-4-(dimethylamino)-5-hydroxy-2-methyloxan-3-yl]oxy}-2,4-dimethyl-3-propoxyoxan-4-yl acetate | image = Miocamycin.png | image_class = skin-invert-image