MDH2
Sign in to saveAlso known as M-MDH, MDH, MGC:3559, MOR1, Malate dehydrogenase 2, EIEE51, DEE51
protein-coding gene in the species Homo sapiens
Gene data
MDH2- Name
- malate dehydrogenase 2
- Type
- protein-coding
- Position
- 76,048,037–76,067,508 (+)
- Aliases
- DEE51, EIEE51, M-MDH, MDH, MGC:3559, MOR1
- Ensembl
- ENSG00000146701
- RefSeq RNA
- NM_001282403.2, NM_001282404.2, NM_005918.4, NR_104165.2
- RefSeq protein
- NP_001269332.1, NP_001269333.1, NP_005909.2
Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013].
Gene Ontology
Biological process
Molecular function
Pathways
Citrate cycle (TCA cycle) - Homo sapiens (human)Cysteine and methionine metabolism - Homo sapiens (human)Pyruvate metabolism - Homo sapiens (human)Glyoxylate and dicarboxylate metabolism - Homo sapiens (human)Aerobic respiration and respiratory electron transportMetabolismMetabolism of proteinsRespiratory electron transportCitric acid cycle (TCA cycle)Mitochondrial protein degradation
via MyGene.info
Gene · Ensembl
malate dehydrogenase 2
- Symbol
- MDH2
- Biotype
- Protein coding
- Organism
- Homo sapiens
- Location
- 7:76,048,037-76,067,508
- Strand
- Forward (+)
- Assembly
- GRCh38
View on Ensembl →
via Ensembl · EMBL-EBI