Metastasis-associated protein MTA2 is a protein that in humans is encoded by the MTA2 gene.
Metastasis-associated protein MTA2 is a protein that in humans is encoded by the MTA2 gene.
MTA2 is the second member of the MTA family of genes. MTA2 protein localizes in the nucleus and is a component of the nucleosome remodeling and the deacetylation complex (NuRD). Similar to the founding family member MTA1, MTA2 functions as a chromatin remodeling factor and regulates gene expression. MTA2 is overexpressed in human cancer and its dysregulated level correlates well with cancer invasiveness and aggressive phenotypes.
Discovered by embedding cosine similarity (sentence-transformers MiniLM, 384-dim).